Holiday Inn St Louis SW - Route 66

About Us

**Renovated
Conveniently located along Historic Route 66, the junction of I-44 and I-270, our hotel has the best to offer our guests.
212 Sleeping rooms, outdoor heated pool with game area, cabanas, firepits, and workout center. Our hotel's Conference Center boasts over 18,000 square feet of meeting space. Guests can enjoy lunch or Dinner at Award-winning Twisted Tree Steakhouse, Wakey, a Breakfast Place now open for a fresh start to your day.
We offer group and Corporate negotiated rates.